Objective: To study the effective substance basis of leaves of Murraya exotica. Method: Preparative TLC

repeated silica gel chromatograph

half-making HPLC were used to separate and purify the isolated compounds

which were structurally identified by the physical and chemical characters and the spectrum data. Result: Eleven compounds were obtained. They were 5

7

3'

4'-tetramethoxyflavone (1)

5

7-dihydroxy-3'

4'

5'-trimethoxyflavone (2)

5-hydroxy-3

7

3'

4'-tetramethoxyflavone (3)

3-hydroxy-5

6

7

4'-tetramethoxyflavone (4)

nobiletin (5)

vanillic acid (6)

ethyl caffeate (7)

5-hydroxy-7

3'

4'-trimethoxyflavone (8)

3

5-dihydroxy-6

7

3'

4'-tetramethoxyflavone (9)

5

6

4-trihydroxy-3

7-dimethoxyflavone (10)

and kaemperol (11). Conclusion: The compounds 3

4

6

9 and 10 were isolated from M.exotica for the first time.