Objective: To clarify the medicinal properties of chemical components in Daturae Flos

and provide scientific basis for the objectivity of new hypothesis theory "One flavor and one property for Chinese medicine

X flavors and Y properties for one medicine (Y≤X)". Method: Male Kunming mice and Wistar rats were randomly divided into normal group

Daturae Flos decoction group

alkaloid components high dose group

low dose group

macroporous resin 50% ethanol elution components high dose group and low dose group. The mice were treated by intragastric administration and the mice in normal group received same volume of normal saline

1 time a day for consecutive 10 days. The effects of Daturae Flos and its chemical components on heart rate

breathing rate

blood pressures

the amount of salivary secretory and body temperature relative to autonomic nervous system were observed as part of the medicinal properties evaluation of Daturae Flos for further research. Result: Compared with the normal group

the Daturae Flos and its alkaloid components had certain effect or effect trend in increasing the heart rate of mice

accelerating the breathing rate of rats

increasing the mean arterial blood pressure in rats

inhibiting salivary secretory in mice and increasing body temperature of rats (P<0.05

P<0.01). Macroporous resin 50% ethanol elution components could promote salivary secretory in mice

and have certain effect on reducing heart rate of mice and reducing breathing rate of rats (P<0.05

P<0.01)

but with no significant effect on mean arterial blood pressure or body temperature in rats. There was certain difference or statistically significant difference between macroporous resin 50% ethanol elution components and alkaloid components in effects on heart rate of mice

breathing rate of rats

mean arterial blood pressure in rats

salivary secretory in mice and body temperature of rats (P<0.05

P<0.01). Conclusion: Daturae Flos and its alkaloid components have warm medicinal properties

while macroporous resin 50% ethanol elution components have cold medicinal properties based on the results and previous research results.