Objective: To observe the effect of Tianma Gouteng decoction on the levels of blood lipid and catalase (CAT) in patients with wind-Yang nuisance type acute cerebral infarction. Method: Sixty-eight patients with wind-Yang nuisance type acute cerebral infarction were randomly divided into treatment group (34 cases) and control group (34 cases). The patients in control group received conventional cerebral infarction treatment(bayaspirin 100 mg qd and lipitor 20 mg qn)

and the patients in the treatment group also received Tianma Goutengyin decoction on the basis of conventional treatment in control group

for a total of 2 treatment courses

with 7 days as one course of treatment.The changes of blood lipid

CAT

neurological function defect scores

and traditional Chinese medicine (TCM) symptom scores were detected before and after treatment. Result: Compared with those of the control group

the levels of total cholesterol(TC)

triglyceride(TG)

low-density lipoprotein cholesterol(LDL-C) and apolipoprotein-B(Apo-B) in the treatment group were reduced(4.08±0.67)

(1.20±0.65)

(1.98±0.24)mmol·L-1

(1.03±0.41)g·L-1

while the level of CAT was increased(20.07±5.83)U·L-1

there was statistical significance between two groups after treatment (P<0.05

P<0.01).The neural function defect score and TCM score were reduced in treatment group(3.65±2.15)

(9.27±7.11)

there was statistical significance between two groups after treatment (P<0.05).The total effective rate was 88.2% in the treatment group and 79.4% in the control group. The treatment group was better than the control group in clinical efficacy (P<0.05). Conclusion: Tianma Gouteng decoction can effectively reduce the levels of blood lipid and increase the CAT level

so that improve the antioxidant capacity in patients with wind-Yang nuisance type acute cerebral infarction.