CAI Cui-zhu, LIU Hai-tao, LYU Ying-chun, et al. Efficacy of Modified Banxia Xiexin Decoction Assisted with Anti-choline Aerosol for Gastroesophageal Reflux Combined with Bronchial Asthma[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(10): 162-165.
CAI Cui-zhu, LIU Hai-tao, LYU Ying-chun, et al. Efficacy of Modified Banxia Xiexin Decoction Assisted with Anti-choline Aerosol for Gastroesophageal Reflux Combined with Bronchial Asthma[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(10): 162-165. DOI: 10.13422/j.cnki.syfjx.2016100162.
Objective: To observe the efficacy of modified Banxia Xiexin decoction assisted with anti-choline aerosol for gastroesophageal reflux combined with bronchial asthma. Method: The 82 patients with gastroesophageal reflux combined with bronchial asthma in our hospital from May 2013 to May 2015 were selected as research objects and randomly divided into observation group and control group
41 cases in each group. Patients in control group were treated with conventional anti-choline aerosol therapy
while patients in observation group received modified Banxia Xiexin decoction on the basis of the treatment of the control group. The symptom scores of gastroesophageal reflux and bronchial asthma control
lung functions
and efficacy of traditional Chinese medicine syndrome were observed and compared before and after treatment in two groups. Result: The symptom scores of gastroesophageal reflux in the observation group after treatment were significantly lower than those before treatment (P < 0.01). The symptom scores of gastroesophageal reflux in observation group were significantly lower than those in the control group at the same period (P < 0.01). The scores of bronchial asthma control were improved after treatment in both groups (P < 0.01)
and the improvement in observation group was more obvious than that in control group (P < 0.01). The first second forced expiratory volume (FEV1%) and maximum expiratory flow rate (PEV%) were significantly increased after treatment in both groups (P < 0.01)
and the increase was more obvious in the observation group than that in the control group (P < 0.01). After treatment for 8 weeks
the efficacy of traditional Chinese medicine syndrome in the observation group was significantly better than that of the control group(P < 0.05). Conclusion: The clinical efficacy of modified Banxia Xiexin decoction assisted with anti-choline aerosol for gastroesophageal reflux combined with bronchial asthma was remarkable
and could effectively improve gastroesophageal reflux symptoms
control bronchial asthma and improve lung functions of the patients.