Objective: To observe the curative effect of Bazhen decoction combined with Tongqiao Huoxue decoction in adjuvant treatment for postoperative brain tumor with Qi-deficiency and blood-stasis syndrome and the influences on serum total superoxide dismutase (SOD)

catalase (CAT) and reduced glutathione (GSH). Method: One hundred and ten patients of postoperative brain tumor treated in department of neurosurgery of our hospital were selected and randomly divided into control group and treatment group (fifty-five cases in each group). Patients of two groups were given routine therapy of anti-infection

symptomatic treatment and nerve nutrition support. Patients of control group were treated with namefene hydrochloride injection by intravenous drip since the first day after operation (8 μg·kg-1

qd). In addition to the therapy of control group

patients of treatment group were treated with Bazhen decoction combined with Tongqiao Huoxue decoction through drip nasogastric tube since the first day after operation

100 mL·d-1. Patients of both groups were treated for two weeks. Syndromes of traditional Chinese medicine(TCM)

Barthel scores

mini-mental state examination (MMSE) and Montreal Cognitive Assessment (MoCA) in both groups were compared. Levels of serum SOD

CAT and GSH were detected in both groups. Result: In the 2nd week after operation

index scores of TCM symptoms in treatment group were obviously lower than those of control group (P < 0.01). In the 2nd and 4th weeks after operation

Barthel scores in treatment group were evidently higher than those of control group (P < 0.01). In the 2nd and 4th weeks after operation

scores of MMSE and MoCA in treatment group were evidently higher than those of control group at the same time points (P < 0.01). In the 2nd week after operation

serum levels of SOD

CAT and GSH in treatment group were remarkably higher than those in control group

with statistical differences (P < 0.01). Conclusion: Bazhen decoction combined with Tongqiao Huoxue decoction in adjuvant treatment for postoperative brain tumor with Qi-deficiency and blood-stasis syndrome could improve clinical symptoms

increase Barthel indexes

and MMSE and MoCA scores

and up-regulate oxidative stress indexes of SOD

CAT and GSH.