Objective: To investigate the studies and ideas on traditional Chinese medicine treatment for male and female infertility based on data mining in Qing dynasty Yulin Recipe Ropy. Method: The Chinese medicine compound recipes for male and female infertility in Qing Dynasty Yulin Recipe Ropy were input to the computer for establishment of a database

and then statistical methods were used to analyze the rule of medication. Result: Totally 117 compound Chinese medicine recipes involving 199 herbs and 964 medication times were collected;core herbs with high-frequency mainly included Moschus

Caryophylli Flos

Aconiti Lateralis Radix Praeparata

Cinnamomi Cortex

Cnidii Fructus

Pericarpium zanthoxyli

Bufonis Venenum

Epimedii Folium. The drugs mainly included the tonic drugs

interior-warming drugs

resuscitation-inducing drugs

and astringent drugs;the herbs with pungent

sweet

and bitter flavors had a cumulative frequency of 80.68%

the herbs with main nature of warming

flatness and coldness had a cumulative frequency of 87.87%

the herbs returning to kidney

spleen

liver

heart

lung

and stomach had a cumulative frequency of 91.39%. Conclusion: Moschus

Caryophylli Flos

Aconiti Lateralis Radix Praeparata

Cinnamomi Cortex

Cnidii Fructus

Pericarpium zanthoxyli

Bufonis Venenum

Epimedii Folium were used with high-frequency in clinical use as recorded in the ancient book;addition and reduction of warming drug and Yang supplementing drug were regarded as the medication characteristics for male and female infertility syndrome.