Objective: To evaluate the clinical efficacy of Qinggan Qushi Huoxue decoction in treatment of patients with nonalcoholic fatty liver. Method: Totally 112 cases of nonalcoholic fatty liver patients were randomly divided into control group (57 cases) and treatment group (55 cases). Control group was given polyene phosphatidylcholine capsules

treatment group was treated with Qinggan Qushi Huoxue decoction. The treatment lasted for two months. Before and after the treatment

patients' digestive system ultrasound

liver function

blood lipid

insulin resistance index (HOMA-IR)

weight index (BMI)

waist circumference and symptom scores were observed. Result: The treatment group showed a total effective rate of 100%

which was higher than control group (P<0.05)

compared with before treatment

two groups of patients showed significant decreases in alanine aminotrans-ferase (ALT)

aspirate aminotrans-ferase (AST)

total cholesterol (TC)

triglyeride (TG)

low density lipoprotein cholesterol (LDL-C)

HOMA-IR

BMI and waist circumference after treatment (P<0.05

P<0.01)

and treatment group was better than control group (P<0.05). Conclusion: Qinggan Qushi Huoxue decoction can significantly alleviate the clinical symptoms of patients with alcoholic fatty liver

reduce their weight index and waistline

alliviate liver function and insulin resistance

and regulate lipid metabolism.