Objective: To observe the clinical efficacy of Qingfei Huazhuo decoction on pulmonary infection in malignant tumors

and explore its possible mechanisms. Method: The 76 patients with pulmonary infection in malignant tumors from January 2014 to February 2015 in integrative department of Henan Cancer Hospital were included in this study

and divided into control group (38 cases) and treatment group (38 cases) by random number table. Patients in control group received routine antibiotics and conventional treatment. Based on the treatment in control group

patients in treatment group received additional Qingfei Huazhuo decoction. Patients were given with corresponding drugs for another 1 week. Then the clinical efficacy was evaluated

routine blood and lung imaging results were observed in both groups

changes in C-reactive protein (CRP) and procalcitonin (PCT) in serum of both groups were detected. Result: The total effective rate was 86.8%in treatment group

higher than 65.8% in control group (P<0.05).The recovery time of body temperature and pulmonary rales in treatment group was less than that in control group (P<0.05)

and the recovery time of routine blood test and lung imaging in treatment group was less than that in control group (P<0.05). After the treatment

both groups showed lower expressions of CRP and PCT in serum (P<0.05)

and the improvement was more obvious in treatment group (P<0.05). Conclusion: Qingfei Huazhuo decoction combined with routine western treatment is more effective than the routine western treatment alone for pulmonary infection in malignant tumors.