CAO Yun, LI Shu-mao, QIU Dong, et al. Analysis on Professor LI Jin-qian's Medication Regularity for Chronic Diastolic Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(16): 215-219.
CAO Yun, LI Shu-mao, QIU Dong, et al. Analysis on Professor LI Jin-qian's Medication Regularity for Chronic Diastolic Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(16): 215-219. DOI: 10.13422/j.cnki.syfjx.2016160215.
Objective: To analyze the composing principles of the prescriptions of professor Li Jin-qian for chronic diastolic heart failure based on Traditional Chinese Medicine (TCM) Inheritance Support System (V2.5). Method: Efforts were made to collect 55 patients' prescriptions of chronic diastolic heart failure cases
enter the data into the TCM inheritance support system
and analyze the data by using frequency analysis
association rules
complex system entropy clustering and unsupervised hierarchical clustering. Result: Totally 64 prescriptions were screened out for the analysis
including 70 herbs. And the total frequency was 2 094.The most frequently used ones were Codonopsis Radix
Astragali Radix
Chuanxiong Rhizoma
Aurantil Fructus
Poria
Platycodonis Radix
Corni Fructus
Paeoniae Radix Rubra
Ophiopogonis Radix
Schisandrae Chinensis Fructus. They were often used at the dosage of 30
50
20
15
30
15
30
20
15
20 g. Among the prescriptions
there were 47 and 22 combinations of three and four herbs with the frequency of more than 50 times
155
67 and 10 combinations of five
six and seven herbs with the frequency of more than 35 times
and six combinations of nine herbs with the frequency of more than 30 times. Through the association rules among herbs
seven core combinations and two new prescriptions were evolved. Conclusion: Professor Li is good at using the principle of supplement Qi and warming Yang in treating chronic diastolic heart failure. Besides
he also applied deficiency-tonifying medicine to nourish the heart
and used blood-activating and heat-clearing medicines to replenish Qi