LIU Bin-bin, JIAN Hui, TIAN Jia-ming, et al. Research Progress and Problem Analysis on Flavoring and Taste Masking Technology for Traditional Chinese Medicine[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(16): 229-234.
LIU Bin-bin, JIAN Hui, TIAN Jia-ming, et al. Research Progress and Problem Analysis on Flavoring and Taste Masking Technology for Traditional Chinese Medicine[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(16): 229-234. DOI: 10.13422/j.cnki.syfjx.2016160229.
Flavoring and taste masking problem of traditional Chinese medicine (TCM) and its preparations has always been a serious challenge
which pharmaceutists usually faced.Through collating
classifying and summarizing literatures from journals at home and abroad in the last decade
this paper expounds the formation of taste and flavoring and taste masking mechanism
then gives a review detailedly of the current research progress about the common flavoring and taste masking techniques
such as adding taste masking agents
bitter blockers
taste buds paralyzing agents and coating
and several emerging innovative techniques
such as solid dispersion technology
ion exchange resin technology
the microencapsulated microsphere technique
inclusion technology and so on
that formed in the process of pharmaceutical development.Then
we made some analysis and discussions about the problems of flavoring and taste masking techniques in TCM.With the patients' demand in drug taste increases
flavoring and taste masking techniques in TCM are paid more attention and have the development trend to comprehensive use various techniques instead of the single technology.But currently
there are still some issues related to taste evaluation
limitations of method selection
industrial production difficult and so on
which need the pharmaceutical workers to study deeply.