Objective: To investigate the clinical effects of Jinshui Liujun Jian and San'ao Fang in assisting the western medicine for acute exacerbation of chronic bronchitis. Method: The 160 patients with acute exacerbation of chronic bronchitis were chosen in the period from May 2012 to May 2014 in Qinghai Hospital of Traditional Chinese Medicine(TCM)

and they were randomly divided into control group (80 patients) with routine western medicine intervention and treatment group (80 patients) with Jinshui Liujun Jian combined with San'ao Fang on the basis of control group treatment. The clinical efficacy

the duration time of clinical signs and symptoms

the TCM syndrome scores

pulmonary function levels

inflammatory cytokine levels and the clinical recurrence rate of two groups were compared. Result: The clinical efficacy in treatment group was significantly better than that in control group (P<0.05). The TCM syndrome scores were significantly reduced after treatment in both groups (P<0.05)

and the scores in treatment group were significantly lower than those in control group after treatment (P<0.05). The duration time of clinical signs and symptoms of treatment group was significantly less than that in control group (P<0.05). The levels of pulmonary function were significantly increased after treatment in both groups (P<0.05)

and the levels in treatment group were significantly higher than those in control group after treatment (P<0.05). The levels of inflammatory cytokine were significantly decreased after treatment in both groups (P<0.05)

and the levels in treatment group were significantly lower than those in control group after treatment (P<0.05). The clinical recurrence rate in treatment group was significantly lower than that in control group (P<0.05). Conclusion: Jinshui Liujun Jian and San'ao Fang in assisting western medicine for acute exacerbation of chronic bronchitis can efficiently alleviate clinical symptoms and signs

shorten the clinical course

improve lung functions

and help to reduce the risk of long-term recurrence.