Objective: To analyze the composing principles of the prescriptions for tic disorders (TD) collected in CNKI and CSPD through Traditional Chinese Medicine(TCM) Inheritance Support System (TCMISS)

in order to provide a reference for clinical treatment of TD. Method: The prescriptions used for TD in CNKI and CSPD from 1998 to 2015 were collected to build a database through TCMISS to make an analysis by association rules and complex system entropy clustering. Then the composing principles of the prescriptions for TD were analyzed. Result: Based on the analysis of 232 cases

the most frequently used drugs included Uncariae Ramulus Cum Uncis

Paeoniae Radix Alba

Bombyx Batryticatus

Glycyrrhizae Radix et Rhizoma and Gastrodiae Rhizoma. And most of these drugs entered the channel of liver. By analyzing the association rules

16 core prescriptions were found

and seven new prescriptions were obtained through the cluster analysis. Conclusion: In the treatment of TD with TCM

invigorating the spleen

calming the liver

reducing phlegm and stopping endogenous wind are the major rules

and recuperating lung is the key. The TCMISS is of great help for the research of TCM prescriptions for TD.