Objective: To evaluate and compare the quality of Zingiberis Rhizoma from different batches and different origins by the grey correlation-TOPSIS method. Method: With the contents of 6-gingerol

8-gingerol

6-shogaol

diacetoxy-6-gingerdiol and 10-gingerol in Zingiberis Rhizoma of different batches and different origins as the evaluation basis

grey correlation-TOPSIS comprehensive evaluation model was established by using MATLAB programming method

and the quality evaluation of Zingiberis Rhizoma from different batches and different origins was ranked. Result: The grey correlation-TOPSIS model evaluation results indicated that the quality of Sichuan Jianwei 20131205

Guangdong Yangjiang 20140221

Guangdong Zhanjiang 20140125

Anhui Bozhou 20131226 was better than that of other batches

consistent with the traditional evaluation results and genuineness

indicating a good repeatability and stability. Conclusion: Grey correlation-TOPSIS comprehensive evaluation method can be well applied to the quality evaluation of traditional Chinese medicine with multiple components

and have the broad prospect in application.