Objective: To observe the clinical efficacy of Qingli Huoxue Jiedu Tang on damp-heat accumulation type gouty arthritis

and explore its action mechanism. Method: The 90 patients with damp-heat accumulation type gouty arthritis were randomly divided into treatment group(60 cases) and control group(30 cases). Patients in treatment group were treated with Qingli Huoxue Jiedu Tang(once in the morning and evening by oral taking)+loxoprofensodium tablets(60 mg po

bid)

patients in control group were treated with loxoprofensodium (60 mg po

bid). Patients were observed for 2 weeks in both groups. The traditional Chinese medicine(TCM) syndrome scores

and the hours of reducing swelling of joint pain were observed

erythrocyte sedimentation rate(ESR)

C-reactive protein(CRP)

uric acid(UA)

visual analogue scale(VAS)

15 meters walking time

routine blood test

routine urine test

safety indexes of liver and kidney functions and other adverse reactions were recorded. Result: The improvement in TCM syndrome scores

the hours of reducing swelling of joint pain

ESR

CRP

UA

VAS

and 15 meters walking time in treatment group was better than that in control group(P<0.05

P<0.01)

and no adverse reaction was present in treatment group. Conclusion: Qingli Huoxue Jiedu Tang can quickly relieve joint swelling

pain and other symptoms

improve joint range of motion

reduce uric acid and inflammatory indexes.