Objective: To analyze the prescription experience of professor BI Rong-xiu for steroid-induced avascular necrosis of femoral head (SANFH) based on traditional Chinese medicine (TCM) inheritance support system(TCMISS). Method: The prescriptions for SANFH were collected. The data was input into the TCMISS

and the composition principles were analyzed by using data mining methods

such as revised mutual information

complex system entropy cluster and unsupervised hierarchical cluster. Result: Based on the analysis of 61 eligible prescriptions

the frequency of each herb and association rules among the herbs were computed

and the most commonly used Chinese herbs

4 core combinations and 6 new prescriptions were determined from the database. Conclusion: Professor BI Rong-xiu focused on the therapy of promoting blood circulation and removing blood stasis

nourishing liver and kidney in the treatment of SANFHT. In addition

according to different accompanied symptoms

professor BI Rong-xiu chose herbs with the efficacy of promoting Qi circulation and relieving pain

supplementing Qi and nourishing yin

and promoting bone

in order to achieve the treatment of both root causes and symptoms. The TCMISS is scientific and practicable to provide a comprehensive and objective analysis on the herbal prescriptions from famous TCM doctors

and so could be used to analyze famous TCM doctors' clinical experience.