中西医结合治疗婴儿巨细胞病毒肝炎临床疗效及安全性Meta分析

李维薇; 杨燕; 谢辉辉; 汪受传

doi:10.13422/j.cnki.syfjx.2016200178

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中西医结合治疗婴儿巨细胞病毒肝炎临床疗效及安全性Meta分析

数据挖掘 | 更新时间：2024-01-04

- 中西医结合治疗婴儿巨细胞病毒肝炎临床疗效及安全性Meta分析
- Meta-analysis on Efficacy and Safety of Integrated Traditional Chinese and Western Medicine Therapy for Infantile Cytomegalovirus Hepatitis
- 中国实验方剂学杂志 2016年22卷第20期页码：178-182
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家自然科学基金项目（81473725）;北京市卫生系统高层次卫生技术人才培养计划项目（2013-2-012）
- DOI：10.13422/j.cnki.syfjx.2016200178
  中图分类号： R725.1
- 纸质出版日期：2016
- 稿件说明：
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李维薇, 杨燕, 谢辉辉, 等. 中西医结合治疗婴儿巨细胞病毒肝炎临床疗效及安全性Meta分析[J]. 中国实验方剂学杂志, 2016,22(20):178-182.

LI Wei-wei, YANG Yan, XIE Hui-hui, et al. Meta-analysis on Efficacy and Safety of Integrated Traditional Chinese and Western Medicine Therapy for Infantile Cytomegalovirus Hepatitis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(20): 178-182.
李维薇, 杨燕, 谢辉辉, 等. 中西医结合治疗婴儿巨细胞病毒肝炎临床疗效及安全性Meta分析[J]. 中国实验方剂学杂志, 2016,22(20):178-182. DOI： 10.13422/j.cnki.syfjx.2016200178.

LI Wei-wei, YANG Yan, XIE Hui-hui, et al. Meta-analysis on Efficacy and Safety of Integrated Traditional Chinese and Western Medicine Therapy for Infantile Cytomegalovirus Hepatitis[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(20): 178-182. DOI： 10.13422/j.cnki.syfjx.2016200178.

摘要

目的：评价中西医结合治疗婴儿巨细胞病毒（cytomegalovirus，CMV）肝炎的临床疗效及安全性。方法：对中国知网数据库，维普中文科技期刊数据库，中国生物医学文献数据库，万方数据库，Pubmed，Cochrane图书馆进行检索。收集有关中西医结合治疗婴儿CMV肝炎的随机对照试验（randomized controlled trial，RCT），根据纳入和排除标准收集文献，进行Meta分析。结果：共纳入12篇RCT，Meta分析结果显示中西医结合治疗该病在总有效率、改善肝功能、促进肝脏回缩以及CMV病毒指标转阴率方面优于对照组。结论：中西医结合治疗婴儿CMV肝炎疗效优于单纯西医治疗，但纳入文献方法学质量普遍偏低，亟需更多高质量的临床试验进一步验证。

Abstract

Objective: To evaluate the clinical effects and safety of integrated traditional Chinese and western medicine for infantile CMV hepatitis. Method: Electronic databases of CNKI

VIP

CBM

Wanfang

Pubmed and Cochrane Library were searched to collect randomized controlled trials(RCTs) of infantile CMV hepatitis. The literatures were screened out according to inclusion and exclusion criteria

and then put into a Meta-analysis. Result: In this study

totally 12 trials were included. According to the Meta-analysis

the treatment group was superior to the control group in evident increases in total effective rate

improvement rate of liver function

promotion of liver retraction to normal

and negative rate of CMV-IgM and CMV-DNA. Conclusion: Compared with western medicine

integrated traditional Chinese and western medicine is superior in treating infantile CMV hepatitis. However

due to the low methodological quality of included trials

more high-quality RCT are required for further verification.

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