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纸质出版日期:2016
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金小千, 袁学雅, 柴铁劬. 助胃膏结合推拿治疗脾胃虚弱型小儿厌食症的临床观察[J]. 中国实验方剂学杂志, 2016,22(24):172-176.
JIN Xiao-qian, YUAN Xue-ya, CHAI Tie-qu. Zhuweigao Combined with Massage for Treatment of Anorexia with Stomach-Spleen Deficiency in Children[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(24): 172-176.
金小千, 袁学雅, 柴铁劬. 助胃膏结合推拿治疗脾胃虚弱型小儿厌食症的临床观察[J]. 中国实验方剂学杂志, 2016,22(24):172-176. DOI: 10.13422/j.cnki.syfjx.2016240172.
JIN Xiao-qian, YUAN Xue-ya, CHAI Tie-qu. Zhuweigao Combined with Massage for Treatment of Anorexia with Stomach-Spleen Deficiency in Children[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(24): 172-176. DOI: 10.13422/j.cnki.syfjx.2016240172.
目的:探讨助胃膏结合推拿对厌食症患儿的体重、体质指数(body mass index,BMI),血清中微量元素钙、铁、锌、血红蛋白,食欲调节因子促食欲激素/瘦素(Ghrelin/Leptin),神经肽Y(NPY),中医临床证候积分的变化及临床疗效。方法:选取1~7岁符合诊断标准的患儿94例,随机分为治疗(助胃膏结合推拿)组与对照(健胃消食口服液)组,各47例。治疗组口服助胃膏3次/日,1丸/次,连续6日为1疗程,共治疗2个疗程;推拿1次/日,连续6日为1疗程,疗程间隔2日,共治疗2个疗程。对照组口服健胃消食口服液,按年龄服用,1岁以下5 mL/次,2次/日;5岁以上每次10 mL,3次/日;余者每次10 mL,2次/日。观察两组治疗前后体重,BMI,血清中微量元素钙、铁、锌、血红蛋白,Ghrelin/Leptin,中医临床证候积分变化及临床疗效。结果:治疗组总有效率为87%,高于对照组总有效率的70%(P<0.05),助胃膏结合推拿可有效改善患儿体重,BMI,血清中微量元素,血红蛋白,食欲调节因子Ghrelin/Leptin值,NPY水平,且疗效优于对照组(P<0.05)。结论:助胃膏结合推拿可有效改善患儿的食欲状况,疗效优于常规中成药。
Objective: To discuss the clinical effects of Zhuweigao combined with massage on anorexia in children
and observed weight
body mass index (BMI)
serum trace elements
calcium
iron
zinc
hemoglobin
Ghrelin/Leptin
Y/Neuropeptide Y (NPY)
traditional Chinese medicine clinical syndrome integral change and clinical efficacy. Method: Totally 94 patients aged between one and seven years old were selected and randomly divided into two groups. The control group was given Jianwei Xiaoshi oral liquid according to age
specifically 5 mL/time for children aged below one year old
bid
10 mL/time for children aged above five years old
tid
and 10 mL/time for the remaining children
bid. The treatment group was treated by Zhuweigao combined with massage
one pill/time
tid
for two weeks for a course. Before and after treatment
weight
body mass index (BMI)
serum trace elements
calcium
iron
zinc
hemoglobin
Ghrelin/Leptin
traditional Chinese medicine clinical syndrome integral change and clinical efficacy of the two groups were observed. Result: The total effective rate of treatment group was 87%
which was higher than 70% in control group
with significant difference (P<0.05). Zhuweigao combined with massage can effectively improve weight
BMI
serum trace elements
hemoglobin
Ghrelin/Leptin and NPY
with a better clinical efficacy (P<0.05). Conclusion: Zhuweigao combined with massage can effectively improve appetite
with a better efficacy than routine Chinese patent medicines.
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