XU Li-yun, YANG Zhi-hong, SUN Xiao-bo. Research Overview of Pharmacokinetic Study of Dammarane-type Ginsenoside[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(1): 220-227.
XU Li-yun, YANG Zhi-hong, SUN Xiao-bo. Research Overview of Pharmacokinetic Study of Dammarane-type Ginsenoside[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(1): 220-227. DOI: 10.13422/j.cnki.syfjx.2017010220.
Ginsenoside has a wide range of pharmacological effects.It has obvious pharmacological effects on the central nervous system
cardiovascular system
immune system
blood and hematopoietic system and so on.Dammarane-type ginsenoside is one of the main effective components of Panax ginseng
and it consists of protopanaxadiol type and protopanaxatriol type.Referring to domestic and foreign research reports of dammarane-type ginsenoside in recent decades
we compare and analyze the literature data in aspects of absorption
distribution
metabolism and excretion.The pharmacokinetic data of ginsenoside Rb1
Rg1
Rc
Rd and Re are summarized.The pharmacokinetic profile and feature of dammarane-type ginsenoside are closely related to its chemical structure.There are significant differences between two dammarane ginsenoside types.This paper reviews the pharmacokinetic characteristics of the two dammarane ginsenoside types
in order to provide references for their further studies.