With the vigorous development of medical hygienic cause and the rapid advance of medical technology in China

modern application of traditional Chinese medicine (TCM) has attracted attention from the world

and its good therapeutic effect has widely recognized at home and abroad. However

in practical clinical application

TCM's adverse reaction reports have gradually increased. Especially

some medicines that were known as non-toxic showed new adverse reactions or toxic reaction during administration; Accordingly

the safety of TCM became a concern. At present

medical workers and pharmaceutical researchers pay more attention to the known toxic herbs in clinical medicines

and could accurately and effectively control them; However

they pay less attention to potentially toxic herbs that have showed adverse reactions but been given no attention. This caused a drug security hole and would lead to major hidden troubles. Therefore

in this paper

a systematic summary was made on traditional Chinese medicines with potential toxicity discovered in recent years

and a comprehensive analysis was conducted for their causes of potential toxicity from perspectives of individual constitution differences

origin

medicinal parts

producing area

processing methods

preparation process

drug dose and course of treatment

with the aim to raise universal attention to application safety of TCM with potential toxicity

provide sufficient basis for in-depth scientific researches for drug toxicity and reference for safe and rational clinical application of TCM

and further improve the safety of TCM in addition to effective clinical application.