Objective: To explore the prescription rules of traditional Chinese medicine in treatment of AIDS and provide objective basis for Chinese medicine treatment of AIDS. Method: Complex network analysis method was used to retrospectively study 2 674 Chinese herbal prescriptions collected from January 2010 to April 2010 in Henan

Anhui

and Hubei. Then the core herbs

compatibility rules and characteristics of commonly used prescriptions for AIDS were analyzed. Result: Multidimensional retrieving results showed that the core TCM herbs for AIDS mainly included Atractylodis Macrocephalae Rhizoma

Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle

Ginseng Radix et Rhizoma

Jujubae Fructus

Glycyrrhizae Radix et Rhizoma

Astragali Radix

Dioscorea Rhizoma

Codonopsis Radix

Lablab semen Album and other Qi tonifying herbs; Angelicae Sinensis Radix

Paeoniae Radix Alba

Rehmanniae Radix Praeparata and other blood tonifying herbs; Poria

Coicis Semen

Amomi Fructus

Alismatis Rhizoma and other dampness clearing herbs. Core prescriptions included Buzhong Yiqi Tang

Xiangsha Liujuntang

and Shenling Baizhu San. Conclusion: The pathogenesis of HIV/AIDS was shown as Qi-blood deficiency and dampness

so the treatment should be replenishing Qi

invigorating spleen and clearing dampness. The results in complex network analysis method in the scientific research and medical records of this paper were basically consistent with the clinical application.