CHEN Shi-tao, ZHA Qin, ZHANG Jun, et al. Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(4): 43-46.
CHEN Shi-tao, ZHA Qin, ZHANG Jun, et al. Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(4): 43-46. DOI: 10.13422/j.cnki.syfjx.2017040043.
Objective: To develope a dynamic optimization technique (DOT) method for the extraction of ginsenosides from ginseng slices. Method: The contents of three major ginsenosides (Rg1
Re and Rb1) were determined by HPLC. The extraction yield
contents of ginsenosides and fingerprints similarity were compared between the DOT method and literature extraction process
to evaluate the feasibility of DOT in optimizing the extraction of ginsenosides from ginseng slices. Result: The dynamic optimization process was extracting for thrice with 8 times by 70% ethanol
and extracting time was 40
20
and 40 minutes in turn with a total extract yield of 41.3 mg·g-1. The extract between DOT process and the literature extraction process was basically the same
but the DOT extraction method could save 63% of extraction time and 60% of power consumption. Conclusion: DOT extraction method can provide shorter extraction time and lower energy cost in the industrial production of ginsenosides from Ginsen Radix et Rhizoma