Objective: To analyze composition principles of kidney-tonifying Chinese medicine prescriptions(KTCMP) in Chinese Pharmacopoeia. Method: Traditional Chinese medicine(TCM) prescriptions for tonifying kidney were collected from the 2015 edition of Chinese Pharmacopoeia. We used TCM inheritance auxiliary system V2.5 to analyze the principles of prescription composition. Result: Soreness and weakness of waist and knees

dizziness andtinnitus are common symptoms of kidney deficiency. KTCMP mainly involes 52 syndromes

with liver and kidney deficiency

spleen and kidney deficiency and deficiency of liver-Yin and kidney-Yin as common syndromes. The 142 KTCMPs contain 290 herbs

and Rehmanniae Radix Praeparata

Poria and Angelicae Sinensis Radix were frequently used. Rehmanniae Radix Praeparata-Poria-Dioscoreae Rhizoma-Angelicae Sinensis Radix is the main core combination. As forliver and kidney deficiency syndrome

the drug combination of Liuwei Dihuangwan and Siwutang could be used and combined with Polygoni Multiflori Radix and Lycii Fructus. As for spleen and kidney deficiency

Sijuntang could be used and combined with Lycii Fructus and Dioscoreae Rhizoma

which was derived from Lingzhu Tusi Wan. Conclusion: Based on the relationship between kidney and other viscera

considerations are given to both deficiency and excess. With kidney tonifying as the core

emphasis was given to pathological changes in kidney deficiency

characteristics of Yin and Yang of kidney and combination of reinforcing and reducing methods.