Objective: To establish a standard for different dosage forms of Ginseng Radix et Rhizoma and provide reference for production practice

based on the study of some threshold values of standard decoction of Ginseng Radix et Rhizoma (SDRG). Method: Twelve batches of SDRG were prepared from representative samples through standard process

then the paste-forming rate

index components content along with their transfer rate

and high performance liquid chromatographic (HPLC) fingerprints similarity were analyzed

compound identification of the common peaks was employed UPLC-Q-TOF/MS;the difference among the slices

the standard decoction and the granule

all from the same batch

were comparatively analyzed to reveal the mass transfer rule in the process. Result: The content of ginsenoside Rb1 and the total amount of ginsenoside Rg1

Re should be not less than 0.282 g·L-1 and 0.529 g·L-1

respectively.Extract rate should be not less than 40%

the fingerprint similarity between batches should be not less than 0.905

and it should be not less than 0.966 when compared with the reference fingerprint R.Ten kinds of saponins were identified in 12 common peaks

the process from slices to standard decoction was the qualitative transfer

while standard decoction to granule was the quantitive change. Conclusion: The standard decoction can act as standard reference object in the production process of formula granule

to guarantee the consistent of final productions through batch charging and process optimization.As to the different forms of Chinese herbal pieces

whether traditional forms or modern ones such as ultramicro piece and formula granule

are almost all dispersed in water in clinical practice;in consideration of the same material basis between the water liquid used and the standard decoction

the standard decoction and its concentration can act as reference material in the aspect of identification and quality control.