基于中医传承辅助平台探讨丁学屏诊治糖尿病的临证经验及用药规律

陆施婷; 陈清光; 徐佩英; 陶枫; 姚政; 陆灏; 丁学屏

doi:10.13422/j.cnki.syfjx.2017070198

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基于中医传承辅助平台探讨丁学屏诊治糖尿病的临证经验及用药规律

数据挖掘 | 更新时间：2024-01-04

- 基于中医传承辅助平台探讨丁学屏诊治糖尿病的临证经验及用药规律
- Analysis on Professor DING Xue-ping's Herbal Administration Experience for Diabetes by Using Traditional Chinese Medicine Inheritance Support System
- 中国实验方剂学杂志 2017年23卷第7期页码：198-205
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家科技支撑计划项目（2012BAI41B05）;国家自然科学基金项目（81503552）;上海市中医药事业发展三年行动计划项目（ZY3-CCCX-2-1003）;上海市中医临床重点实验室项目（14DZ2273200）
- DOI：10.13422/j.cnki.syfjx.2017070198
  中图分类号： R249;R259
- 纸质出版日期：2017
- 稿件说明：
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陆施婷, 陈清光, 徐佩英, 等. 基于中医传承辅助平台探讨丁学屏诊治糖尿病的临证经验及用药规律[J]. 中国实验方剂学杂志, 2017,23(7):198-205.

LU Shi-ting, CHEN Qing-guang, XU Pei-ying, et al. Analysis on Professor DING Xue-ping's Herbal Administration Experience for Diabetes by Using Traditional Chinese Medicine Inheritance Support System[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(7): 198-205.
陆施婷, 陈清光, 徐佩英, 等. 基于中医传承辅助平台探讨丁学屏诊治糖尿病的临证经验及用药规律[J]. 中国实验方剂学杂志, 2017,23(7):198-205. DOI： 10.13422/j.cnki.syfjx.2017070198.

LU Shi-ting, CHEN Qing-guang, XU Pei-ying, et al. Analysis on Professor DING Xue-ping's Herbal Administration Experience for Diabetes by Using Traditional Chinese Medicine Inheritance Support System[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(7): 198-205. DOI： 10.13422/j.cnki.syfjx.2017070198.

摘要

目的：运用“中医传承辅助平台（V2.5）”，分析“疾病-证候-治法-中药”之间的关系，探讨丁学屏教授诊治糖尿病及其慢性并发症的临证经验及用药规律，总结丁学屏教授学术经验。方法：通过临床医案采集，结合软件的分析系统，采用频次统计法，统计得出医案症状、证候、治法出现频次，使用中药性味归经频次；采用关联规则分析法、聚类分析法、改进的互信息法、复杂系统熵聚类、无监督的熵层次聚类等高级数据挖掘方法，统计得出处方中药物组合使用频次及药物之间的关联规则。结果：本研究对39例糖尿病阴虚热盛证进行分析，高频药物有地骨皮、黄连、山药、地黄、知母等，药物组合有桑叶、黄连，桑白皮、黄连，地黄、桑叶、黄连等。对29例糖尿病气阴两虚证进行分析，高频药物有黄连、山药、地黄、地骨皮、知母等，药物组合有黄连、地骨皮，地黄、地骨皮、黄连，地骨皮、山药、黄连等。结论：辨治糖尿病，兼顾“本虚标实”，治拟“清热、滋阴”并举，多用甘寒生津之品清热救液。

Abstract

Objective: Analyzing the ‘disease-syndrome-treatment-medicine’ experience of professor Ding for diabetes and its chronic complications by using Traditional Chinese Medicine(TCM) Inheritance Support System(V2.5). By analyzing the data

we summarize the Professor Ding's academic experience. Method: Through collecting the standard clinical cases

combined with the software analysis system

we analyze the composing principles by using datamining methods such as frequency statistics

revised mutual information

association rules analysis

cluster analysis

improvement of mutual information

complex system entropy clustering

unsupervised hierarchical clustering entropy and so on. Result: Characteristics of simple diabetes. Based on the analysis of 39 cases of simple diabetic ‘Yin deficiency and heat Syndrome’

the highest-frequency used drugs were Lycii Cortex

Rhizoma Coptidis

Dioscoreae Rhizoma

Rehmanniae Radix

Anemarrhenae Rhizoma and so on. The highest-frequency used drug combinations were Mori Folium

Rhizoma Coptidis;Mori Cortex

Rhizoma Coptidis; Rehmanniae Radix

Mori Folium

Rhizoma Coptidis and so on. Based on the analysis of 29 cases of ‘Qi and Yin deficiency syndrome’

the highest-frequency used drugs were Rhizoma Coptidis

Dioscoreae Rhizoma

Rehmanniae Radix

Lycii Cortex

Anemarrhenae Rhizoma and so on. The highest-frequency used drug combinations were Rehmanniae Radix

Lycii Cortex; Rehmanniae radix

Lycii Cortex

Rhizoma Coptidis; Lycii Cortex

Dioscoreae Rhizoma

Rhizoma Coptidisand so on. Conclusion: Treating simple diabetes focus on the ‘asthenia in origin and asthenia in superficiality’

‘remove heat and nourish Yin is important’

we often use herbs which aresweet-flavored and cold-natured.

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