Objective: To observe the clinical efficacy of traditional Chinese medicine(TCM) of invigorating kidney and promoting blood circulation on the inflammatory factors of patients with intrauterine adhesion after surgery

and explore its mechanism. Method: The 123 patients were randomly divided into control group (61 cases) and observation group (62 cases). Patients in control group were treated by sequential application of Estrogen-progesterone

and those in observation group were also given Bushen Huoxue decoction for two weeks in addition to the therapy of control group. Renal and liver functions of both groups were monitored. Hemoglobin (HGB)

partial thromboplastin time (APTT)

D-dimer (DD) and serum concentration of tumor necrosis factor-α (TNF-α)

interleukin-6 (IL-6) before and after treatment were measured in two groups. The incidence of adhesion within three months was compared. Result: The level of DD was significantly decreased

and HGB were higher after treatment in observation group than that in control group (P<0.01). The levels of TNF-α and IL-6 were lower at the 3rd

7th day after the operation (P<0.01). The clinical curative effect of observation group was significantly higher than that of control group (P<0.05). The incidence of adhesion within three months of observation group was also lower than control group (12.90% vs 27.87%

P<0.05). Conclusion: Bushen Huoxue decoction may improve clinical efficacy and prevent postoperative adhesion in patients by improving uterine microcirculation and inhibiting inflammatory reaction.