Objective: To examine the content of linderane and norisoboldine in different parts of Linderae Radix

and make a discriminant analysis by fourier transformation infrared spectroscopy. Method: Linderae Radix was divided into three groups

namely skin group

peeling group and original group. According to the chromatographic conditions for linderane and norisoboldine of Linderae Radix in Chinese Pharmacopoeia

HPLC was used to examine the content of linderane and norisoboldine in different parts of Linderae Radix. Near-infrared spectra of skin group

peeling group and original group samples were analyzed through principal component analysis. The principal components analysis model was developed based on the spectrum band of 5 053.85-4 115.54 cm-1 with ‘SNV+spectrum+F-G’. Result: Three samples from the three parts of Linderae Radix were divided into three categories by the model of FT-NIR qualitative discriminant analysis

and there was a clear boundary between the different parts. According to the findings of HPLC analysis

the sequence of the content of linderane and norisoboldine in different parts from high to low was skin group > original group > peeling group. Conclusion: The results of HPLC analysis showed that the content of linderane and norisoboldine in Linderae Radix skin group was higher

and that of the peeling group was the lowest. FT-NIR analysis further proved the differences in the quality of different part Linderae Radix. The two analysis methods provide the scientific basis for weather Linderae Radix shall be peeled or not during processing.