Objective: To find out the hazard factor of toxic heat syndrome of acute myocardial infarction (AMI) and the causes. Method: Clinical data of the patients who were diagnosed as acute myocardial infarction at our hospital were collected retrospectively. We collected the patients' traditional Chinese medicine syndrome and divided the patients into toxic heat group and non-heat toxin group. We analyzed the general clinical data and the hospitalization prognosis of both groups. Logistic regression analysis was made to find out the hazard factor of toxic heat syndrome of acute myocardial infarction. Result: Totally 322 patients were enrolled in this study

including 42.20% of heat toxin patients (136 patients) and 57.8% of non-heat toxin patients (186 patients). In terms of the index of the culprit vessel and left ventricular ejection fraction and left ventricular diastolic volume

the heat toxin group was severer than the non-heat toxin group (P<0.05)

but there was no significant difference in the hospitalization cardiovascular death between the two groups. According to the univariate analysis

toxic heat syndrome in the AMI patients were the multiple cardiovascular risk factors for people with smoking

spicy and high-fat diet

diabetes

hyperlipidemia (P<0.05). Smoking

low-density lipoprotein and triglyceride were the independent risk factors according to the logistic regression analysis

and the odds ratios were 1.755

1.637

1.483. Conclusion: The causes of the toxic heat syndrome on acute myocardial infarction include smoking and hyperlipidemia. There is no significant difference in the hospitalization prognosis between the two groups

but the heat toxin group is severer than the non-heat toxin group in the degree of ventricular remodeling.