Objective: To investigate the clinical efficacy of Yaoshi Xinbao decoction combined with western medicine in the treatment of coronary heart disease and observe its effect on serum homocysteine (HCY) level and blood coagulation function. Method: The 200 patients with blood stasis syndrome coronary heart disease from January 2015 to January 2016 in Department of cardiology of our hospital were randomly divided into control group (102 cases) and observation group (98 cases). Patients in control group were treated with conventional western medicine

and patients in observation group received additional Yaoshi Xinbao decoction based on the treatment in control group for 8 weeks. The two groups of patients were compared for serum homocysteine (HCY) and coagulation function (prothrombin time

activated partial thromboplastin time

fibrinogen). Result: The improvement degree of coagulation function and serum HCY level in observation group was better than that in control group after treatment (P<0.05); observation group could significantly reduce the serum HCY level in patients with CHD (P<0.05)

and regulate the blood coagulation function (P<0.05)

with significant differences between the groups

especially in the improvement of coagulation function (P<0.05). Control group had no significant differences before and after treatment. Conclusion: Yaoshi Xinbao decoction combined with western medicine has clear clinical curative effect in treatment of coronary heart disease

which can effectively reduce the level of HCY in CHD patients and regulate blood coagulation function

so it is worthy of clinical promotion.