基于数据挖掘治疗肾虚型月经病的用药分析

杜萍; 庞会明; 卢金福

doi:10.13422/j.cnki.syfjx.2017150211

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基于数据挖掘治疗肾虚型月经病的用药分析

数据挖掘 | 更新时间：2024-01-04

- 基于数据挖掘治疗肾虚型月经病的用药分析
- Analysis on Medication Rules of Emmeniopathy with Kidney Deficiency at Department of Gynecology Based on Data Mining
- 中国实验方剂学杂志 2017年23卷第15期页码：211-215
- 作者机构：
- 作者简介：
- 基金信息：
  
  江苏省高校优势学科建设工程项目（中药学）;南京药学会常州四药医院药学科研基金项目（2015YX010）
- DOI：10.13422/j.cnki.syfjx.2017150211
  中图分类号： R271.11
- 纸质出版日期：2017
- 稿件说明：
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杜萍, 庞会明, 卢金福. 基于数据挖掘治疗肾虚型月经病的用药分析[J]. 中国实验方剂学杂志, 2017,23(15):211-215.

DU Ping, PANG Hui-ming, LU Jin-fu. Analysis on Medication Rules of Emmeniopathy with Kidney Deficiency at Department of Gynecology Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(15): 211-215.
杜萍, 庞会明, 卢金福. 基于数据挖掘治疗肾虚型月经病的用药分析[J]. 中国实验方剂学杂志, 2017,23(15):211-215. DOI： 10.13422/j.cnki.syfjx.2017150211.

DU Ping, PANG Hui-ming, LU Jin-fu. Analysis on Medication Rules of Emmeniopathy with Kidney Deficiency at Department of Gynecology Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(15): 211-215. DOI： 10.13422/j.cnki.syfjx.2017150211.

摘要

目的：探讨南京中医药大学附属医院（江苏省中医院）妇科治疗肾虚型月经病用药规律，为临床治疗及新药研发提供指导。方法：收集江苏省中医院妇科门诊2016年5月到2016年10月治疗肾虚型月经病处方1 075张，利用微软Excel强大的排序、筛选和统计功能进行数据挖掘，统计各中药的用药比例。结果：使用频率在50%以上的单味中药有续断、茯苓、白芍（炒）、山药、丹参、山茱萸（酒）、赤芍、菟丝子8种。使用频率在30%~50%的中药有当归、白术（麸炒）、香附（醋）、熟地黄、牡丹皮、杜仲（盐）6种。使用频率在10%以上43种中药中，以中药学常规分类，使用率较高的依次是补益药、活血化瘀药，其他为清热药、理气药等。以药性分类，使用率由高到低依次是温性药、平性药及寒性药，温性药的使用率显著高于平性药、寒性药。药对使用以茯苓-山药为最高（51.2%），其次是山药-山茱萸（47.7%），白芍-赤芍（39.5%）等。结论：我院妇科治疗肾虚型月经病擅用续断、茯苓、白芍（炒）、山药、丹参、山茱萸（酒）、赤芍、菟丝子等单味药，药对则以茯苓-山药，山药-山茱萸，白芍-赤芍应用见长。这些药物的应用充分体现了补益、健脾、活血、祛寒的治法治则，反映了治疗肾虚型月经病的用药规律。

Abstract

Objective: To investigate the medication rules of emmeniopathy with kidney deficiency at Department of Gynecology of our hospital. Method: A total of 1 075 prescriptions of outpatient of menstrual disorders were collected from Department of Gynecology of Jiangsu Province Traditional Chinese Medicine (TCM) Hospital from May 2016 to October 2016

and the proportion of herbs was analyzed by using the powerful sorting

screening and statistics functions of Microsoft Excel for data mining. Result: The utilization rate of 8 TCM herbs was more than 50%

which were Dipsaci Radix

Poria

Paeoniae Radix Alba (fried)

Dioscoreae Rhizoma

Salviae Miltiorrhizae Radix et Rhizoma

Corni Fructus (fried with wine)

Paeoniae Radix Rubra and Cuscutae Semen. The utilization rate of 6 TCM herbs was between 30%-50%

which were Angelicae Sinensis Radix

Atractylodis Macrocephalae Rhizoma (fried with wheat bran)

Cyperi Rhizoma (fried with vinegar)

Rehmanniae Radix Praeparata

Moutan Cortex

and Eucommiae Cortex (fried with salt). According to conventional classification of Chinese materia medica

herbs with the higher rate were tonics and those for activating blood stasis. The others were herbs for regulating Qi and clearing heat. On the basis of the utilization rate

drug natures from high to low were warm

neutral and cold

respectively. The utilization rate of warm herbs was significantly higher than that of neutral and cold herbs. The utilization rate of herb pair of Poria-Dioscoreae Rhizoma (51.2%) was higher than that of Dioscoreae Rhizoma-Corni Fructus (47.7%) and Paeoniae Radix Alba-Paeoniae Radix Rubra (39.5%). Conclusion: Our Department of TCM Gynecology has generally treated emmeniopathy with kidney deficiency with such single herbs as Dipsaci Radix

Poria

Paeoniae Radix Alba (fried)

Dioscoreae Rhizoma

Salviae Miltiorrhizae Radix et Rhizoma

Corni Fructus (fried with wine)

Paeoniae Radix Rubra and Cuscutae Semen

herb pairs such as Poria-Dioscoreae Rhizoma

Dioscoreae Rhizoma-Corni Fructus and Paeoniae Radix Alba-Paeoniae Radix Rubra. The application of these herbs fully indicated the therapeutic principles of tonics and herbs strengthening spleen

activating blood stasis and dispelling cold

and the medication rules for treating emmeniopathy with kidney deficiency in our hospital.

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