Objective: To study on volatile components in different processed products of Bupleuri Radix

and to reveal the processing rule of ‘don't make a fire’.Method:Analysis was adopted by headspace injection combined with GC-MS

HP-5 MS column was used;the initial temperature was 60℃

which maintained 2 min

with the pace of 10℃ · min-1 to become 250℃

which maintained 10 min.Ionization mode was electron impact(EI)

electron energy was 70 eV

the ion source temperature was 230℃

quadrupole temperature was 150℃

injection volume was 1 μL

the relative content of volatile components were determined by area normalization method

and its compounds were identified by headspace injection combined with GC-MS.Result: The volatile components in crude Bupleuri Radix accounted for 89.21% of total detective

turtle blood mixed Bupleuri Radix occupied 97.37%

turtle blood fired Bupleuri Radix occupied 98.00%

Bupleuri Radix processed by wine occupied 94.90% and Bupleuri Radix processed by vinegar occupied 98.88%.The processed products were a total of pentanal

1-pentanol

hexanal

heptaldehyde and other ingredients

hexanal was the highest components in crude Bupleuri Radix

turtle blood mixed Bupleuri Radix and turtle blood fired Bupleuri Radix.The contents of pentanal

heptaldehyde and 2-pentylfuran in turtle blood fired Bupleuri Radix were higher than those of the other processed products.Hexanoic acid was the unique component in Bupleuri Radix processed by vinegar.Conclusion: The volatile components in different processed products of Bupleuri Radix have great difference

which is an important material basis for their efficacy.