Objective: To study the chemical constituents from the mature fruits of Solanum muicatum. Method: S. muicatum dry fruits were heated and extracted by using 95% ethanol

and then were extracted with petroleum ether

ethyl acetate and n -butanol in turn. Ethyl acetate extract fraction of S. muicatum 95% ethanol extract was isolated and purified by using chromatography on silica gel

Sephadex LH-20 column chromatography and preparative HPLC methods. The structures of the compounds were then identified by analysis of NMR and spectroscopic data by comparison with those reported on the literature. Result: Seven compounds were isolated from 95% ethanol andthey were identified as solasonine(1)

solamargine(2)

solasodine(3)

quercetin(4)

naringenin(5)

ferulic acid(6)

and ursone(7). Conclusion: All of the compounds were obtained from this plant for the first time

providing certain chemical basis and foundation for the comprehensive development and the search for natural plant anti-inflammatory and antitumor active substances