Objective: To observe the clinical efficacy of Dongbing Xiazhi Sanfu plaster on lung-kidney deficiency syndrome in remission stage of bronchial asthma

and investigate its mechanism. Method: From January 2013 to June 2014

180 patients with bronchial asthma in remission stage in our hospital were collected and then were randomly divided into experimental group and control group

90 cases in each group.Patients in control group received conventional western medicine treatment such as symbicort turbuhaler

and patients in experimental group received Dongbing Xiazhi Sanfu plaster on basis of treatment in control group for three years.The changes of symptom scores

pulmonary function before and after treatment

and the recurrence rate were observed. Result: The plaster fell off in one case of each group during follow-up period.The total effective rate was 94.38% in treatment group

and 75.28% in control group (P<0.05).Two years later

the forced expiratory volume in one second (FEV1)

FEV1%

peak expiratory flow (PEF) were improved in both groups

and the improvement of PEF in experimental group was better than that in control group (P<0.05).Three years later

the three indicators were improved significantly in both groups (P<0.05)

and the number of acute attacks in observation group was significantly lower than that in control group (P<0.05).Safety testing showed that twenty-one patients in experimental group had skin blisters

but they were absorbed after local treatment

with no impact on next acupoint application

and there was no serious adverse events. Conclusion: Dongbing Xiazhi Sanfu plaster can significantly reduce the symptoms during the onset in patients with bronchial asthma

such as asthma

chest tightness and cough

improve the lung function

reduce the number of asthma attacks

and improve the cure rate without serious adverse events.It indicates that Dongbing Xiazhi Sanfu plaster can improve the prognosis of bronchial asthma

worthy of widespread clinical application.