WANG De-jun, LI Lu-kai, ZHANG Hui. Effect of Jiawei Erchentang on Polycystic Change, Endocrine and Metabolism in Patients with Polycystic Ovary Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(24): 190-195.
WANG De-jun, LI Lu-kai, ZHANG Hui. Effect of Jiawei Erchentang on Polycystic Change, Endocrine and Metabolism in Patients with Polycystic Ovary Syndrome[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(24): 190-195. DOI: 10.13422/j.cnki.syfjx.2017240190.
Objective: To study the effect of Jiawei Erchentang polycystic change
endocrine and metabolism in patients with polycystic ovary syndrome (PCOS). Method: A total of 157 cases of PCOS patients treated in our hospital from March 2015 to March 2016 were selected in this study
and divided into two groups by the random number table
with 78 cases in clinical group and 79 in control group. Patients in control group were treated with cyproterone acetate tablets. In addition to the therapy of the control group
the clinical group was also given Jiawei Erchentang. Then efficacy
polycystic change
endocrine and metabolism were compared. Result: The total effective rate of control group was 81.01%
while that of clinical group was 94.87%
with a significant difference (P<0.05). Compared with before treatment
ovarian volume and ovarian follicle conditions of two groups after treatment decreased (P<0.05). Compared with control group
ovarian volume and ovarian follicle conditions of the experimental group were lower (P<0.05). Compared with before treatment
luteotropic hormone (LH)
follicle-stimulating hormone (FSH) and testosterone (T) of two groups after treatment decreased
while estradiol (E2) increased (P<0.05). Compared with control group
LH
FSH and T of the experimental group were lower after treatment
while E2 was higher (P<0.05). Compared with before treatment
glucolipid metabolism indexes
including hemoglobin Alc (HbA1c)
fasting insulin (FINS)
insulin resistance index (HOMA-IR)
total cholesterol (TC)
triglycerid (TG) of two groups after treatment decreased (P<0.05). Compared with before treatment
visfatin (VF) and leptin (LEP) of two groups after treatment decreased
while adiponectin (APN) increased (P<0.05). Compared with control group
VF and LEP of the experimental group were lower after treatment
while APN was higher (P<0.05). Conclusion: Jiawei Erchentang has a better effect on PCOS