Objective:To study the composition

antioxidant activity and antimicrobial activity of liposoluble constituents from Taraxacum mongolicum leaves. Method:Soxhlet extraction was used to extract the liposoluble constituents from dandelion leaves (LCDLs)

and their compositions were studied by using GC-MS. The antioxidant activity was determined by phosphomolybdate complex method

pyrogallol autoxidation spectrophotometry and Fenton oxidation method

while the antimicrobial activity was determined by the slip method and microporous diffusion method. Result:There were about 36 kinds of LCDLs extracted by this method. With the increase of sample concentration

the total antioxidant activity of LCDLs and their clearance for the superoxide anion (O2-·) and hydroxyl radical (·OH) were all enhanced. However

their total antioxidant activity and scavenging effect on the O2-·and·OH were lower than those of Vit C(VC). LCDLs had good antibacterial and bactericidal effect against Staphylococcus aureus

Escherichia coli

Bacillus subtilis and Candida albicans

with MIC and MBC of 0.5

1.72

2.46

3.58 g·L-1 and 0.84

1.88

3.62 and 4.74 g·L-1 respectively. Especially

it showed best antimicrobial and bactericidal effect against S. aureus. Conclusion:This study showed that the LCDLs were complex and had a certain antioxidant activity and good antimicrobial effect

providing reference and basis for the development and utilization of T. mongolicum resources.