Objective:To study on the accumulation of secondary metabolites in leaves of Apocynum ventum and Poacynum hendersonii

reveal the main difference s between them and clarify certain regularity. Method:In July

August and September

33 samples in different habitats were collected

and then the contents of chlorogenic acid

rutin

hyperoside

isoquercetin

astragulin

quercetin and kaempferol in leaves were detected by ultra performance liquid chromatography (UPLC). Finally

the data were analyzed by descriptive statistics

correlation analysis and cluster analysis. Result:The standard deviation of chlorogenic acid content in 17 samples of A. ventum and 16 samples of P.hendersonii was 13.24 and 12.59 mg·g-1 respectively

and the standard deviation of rutin

hyperoside

isoquercetin

astragulin

and kaempferol of them was 1.00

4.76

3.62

0.23 mg·g-1 and 0.27

0.82

0.59

0.03 mg·g-1.The main components content in leaves of Poacynum displayed low (July)-high(August)-low(September)

while Apocynum displayed gradual increase in these three months. 33 samples with distance between clusters equal to 15

can be divided into four categories. Conclusion:Considering from the stability of the main component content

Apocynum leaf was preferred in development. Although the main compositions of Apocynum leaves and Poacynum leaves had certain differences

the content of main chemical composition was not effective to distinguish the Apocynum and Poacynum because of the influence by habitat and the harvest season. In case of no strict requirements

especially when focusing on the main compounds

they can be used alternatively. Altay

Jeminay

Ili and Changchun would be the better planting areas in respect of planting areas.