Diabetic nephropathy (DN) is one of the important chronic complications of diabetic patients. Because the most important feature of diabetic is glomerular cell sclerosis

type 1 and type 2 diabetes have a certain probability of suffering from DN

which may finally develop to kidney necrosis. Life and health of diabetic patients are directly threatened by DN. Benefited from the rapid advance of modern medical technology

fewer and fewer diabetic patients died of ketoacidosis. Currently

the main cause for diabetes deaths is various complications of diabetes

such as DN and cardiovascular disease caused by diabetes. DN is the most serious chronic microvascular complication for diabetic patients

as well as one of important causes for the death of DN. The inflammatory response process plays a very important role in the development and progress of DN. At present

many studies have reported relevant reviews of diabetic nephropathy

finding that diabetic nephropathy-associated inflammatory factors mainly include C-reactive protein

transforming growth factor-β

DN

inflammatory signaling pathway nuclear factor(NF)-κB signal transduction pathway and mitogen-activated protein kinase(MAPK) signal transduction pathway. This paper summarizes the pathogenesis of DN and the prevention and treatment with traditional Chinese medicine

in order to provide a reference for early prevention of DN and later intervention and treatment.