Objective:To observe the clinical efficacy of enema with Changfengyin in acute radioactive rectitis caused by radiotherapy in treatment of cervical cancer with syndrome of intestinal wind injuring collaterals and its effect on serum interleukin (IL)-1

IL-6 and tumor necrosis factor-alpha (TNF-α). Method:A total of 84 eligible patients were randomly divided into two groups

with 42 cases in each group. The treatment group was given retention enema with Changfengyin; whereas control group was given retention enema with montmorillonite powder. Before and after invention

clinical symptoms

congestion

edema

Karnofsky performance status (KPS)

serum IL-1

IL-6 and TNF-α were observed

and the clinical efficacy was evaluated. Result:After treatment

TCM symptoms scores and rectal mucosa score

serum IL-1

IL-6

TNF-α in treatment group were lower than those of the control group (P<0.05). The treatment group's KPS score after treatment was higher than that of the control group

with significant differences (P<0.05). The total effective rates of treatment group and control group were 90.48% and 76.16% respectively

with a significant difference (P<0.05). Conclusion:Changfengyin can effectively alleviates the rectal injury clinical symptoms of malignant pelvic tumor patients

improves rectal mucosa and patient function

and effectively regulate serum IL-1

IL-6

TNF-α levels

and is worth promotion and application.