Objective: To find out the correlation between information groups of delivery dose and aerosol particle size of Reduning inhalation solution. Method: Taking chlorogenic acid and geniposide as index components

the delivery dose uniformity was determined by a breathing simulator and the aerodynamic particle size distribution was measured by a new generation of particle impactor.Realtime particle size distribution was monitored by a laser diffractometers.The correlation analysis between information groups of delivery dose and aerosol particle size was investigated. Result: Most primitive variables of two sets had good intra-class correlations

but the inter-group correlation was not as good as intra-class correlation.After the canonical correlation analysis

two pairs of canonical variables had significant correlations with correlation coefficients being 0.998 and 0.955

respectively.Almost 90% information of delivery dose group and more than 70% information of particle size group could be elucidated by the two pairs of canonical variables. Conclusion: There is a good intra-class correlation for each of delivery dose group and particle size group

but the correlation between two sets is not so good.Canonical variables perform better inter-group correlation by comparing with original variables

indicating there is a certain correlation between delivery dose and aerosol particle size of Reduning inhalation solution.Furthermore

original variables of these two sets can be well predicted by the two pairs of canonical variables extracted.