Objective:To study the clinical efficacy of Bushen Tiaochong decoction combined with routine western medicine in treating patients with kidney deficiency and blood stasis type recurrent spontaneous abortion (RSA)

and its effect on Th1/Th2 cytokines balance. Method:Totally 122 cases of RSA patients treated in our hospital from March 2015 to August 2016 were selected and divided into two groups according to the group sequential design

with 61 cases in clinical group and 61 in control group. Patients in control group were treated with Dydrogesterone tablets; in addition

those in clinical group were also given Gexia Zhunyu decoction. Then the clinical efficacy

β-human chorionic gonadotropin (β-HCG)

progesterone (P)

interleukin-2 (IL-2)

interleukin-10 (IL-10)

IL-2/IL-10 and blood rheology were compared. Result:The total effective rate of the control group was 80.33%

while that of the clinical group was 91.80%. There was a significant difference (P<0.05). Compared with before treatment

β-HCG increased after treatment (P<0.05). Compared with control group

β-HCG and P of clinical group were higher than those of control group

with statistically significant differences (P<0.05). Compared with before treatment

IL-10 of the two groups after treatment increased

while IL-2 and IL-2/IL-10 decreased (P<0.05). Compared with control group

the value of IL-10 in patients of the experimental group was higher after treatment

while IL-2 and IL-2/IL-10 were lower (P<0.05). After treatment

both groups of CPID patients showed significant reduction in blood viscosity at high/low shear rate

erythrocyte aggregation index and hematocrit

with statistically significant differences (P<0.05). Conclusion:Bushen Tiaochong decoction is very effective in treating RSA. It can significantly improve β-HCG and P

balance Th1/Th2 cytokines and improve microcirculation

thus is worth promotion in clinic.