The increasing pressure of life as well as complex and changeable of economic and social environment have led to high incidence of emotional illness

such as social anxiety disorders

depression. Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) cause serious physical and psychological distress

disrupt interpersonal communication and reduce quality of life and happiness index. Suicide is also possible in severe cases

so this disease prevention is imminent. Related research proves that many biochemical factors are involved in the PMS(PMDD) disease process

and personality

physical and many other psychological and social factors are also involved although the researches are not deep enough and unclear in mechanism exploration. In recent years

Chinese medicine has achieved remarkable efficacy in the prevention and treatment of emotional diseases

and has been recognized by the academic circles. In traditional Chinese medicine (TCM)

stagnation of liver Qi is PMS(PMDD) pathogenesis

caused by liver-Qi depression

characterized by depressive mood

manifested as depression

down in spirits and negative attitude. There is a cohort association with depression. With the gradual deepening of the mechanism research

the brain center is considered to be the ultimate mechanism. The brain is the center of the body

which plays an important role in the occurence

development and treatment of the disease

and can be used for precise positioning of the brain center abnormalities. Therefore

it is very important to identify the exact pathogenesis. At the same time

the mechanisms of the prescriptions widely used in the market are still not clear

and whether they have reached the lesion is still unknown. However

in the context of ‘precision medicine’

accurate alignment of the brain center is achieved through the modern scientific and technological means

with great significance in clarifying the drug mechanism and efficacy

developing new drugs with precise targets

and completely curing the disease.