Objective:To observe the efficacy of Bushen Qingre Paishi decoction for the post-operative prevention and treatment of the renal deficiency and humid heat type infectious renal calculus. Method:Totally 70 patients were randomly divided into two groups:treatment group and control group

35 cases in each group. The treatment group orally took Bushen Qingre Paishi decoction that was modified from Bazhengsan and Shenqiwan

while the control group orally took levofloxacin

ceftizoxime and ammonium chloride. Calculus recurrence and changes in negative rate of urine culture

urine pH value

24 h urine biochemical analysis

serum calcium

serum phosphorus

serum creatinine were observed 4 weeks after treatment. Result:The total effective rate of the treatment group was 88.6%

which was significantly higher than 68.6% of control group (P<0.05). The improvement in 24 h urine citric acid and the reduction in 24 h urine phosphorus of control group were more significant than those of control group after administration (P<0.05)

but with no obvious difference in infection control and reduction of urine pH value between two groups. The two groups showed no statistically significant difference in 24 h urine oxalate

24 h urine calcium and serum calcium

serum phosphorus

serum creatinine after administration. Conclusion:Bushen Qingre Paishi decoction has a satisfactory effect for the post-operative treatment of renal deficiency and humid heat type infectious renal calculus

and can also prevent the recurrence of infectious renal calculus and provide new ideas for treating infectious kidney stones

with a good study prospect.