Objective: To compare the quality difference between Mahuang Xixin Fuzitang (MXF) prepared by different processed products of Aconiti Lateralis Radix Praeparata for exploring the scientificalness of selection of processed products specification in classic Chinese materia medica recipe. Method: By taking effect-toxic components in MXF as evaluation indexes

this article investigated MXF decoction prepared by five different processed products of Aconiti Lateralis Radix Praeparata from the quantitative determination of effect-toxic components in MXF. Result: After multivariate statistical analysis

six characteristic constituents were identified as kakuol

methyl eugenol

asarinin

mesaconitine (MA)

hypaconitine (HA) and aconitine (AC)

respectively.Compared with other processed products

the processed product prepared by stir-frying had the lower content of diester alkaloids and the highest level of monoester alkaloids. Conclusion: There are differences on the content of effect-toxic components in MXF prepared by different processed products of Aconiti Lateralis Radix Praeparata

which can provide a reference for making the past serve the present of classic Chinese materia medica recipe.