Objective: To investigate the chemical constituents of Solanum septemlobum. Method: The ethyl acetate fraction of 95% ethanol extract of S. septemlobum was isolated and purified by silica gel column chromatography

Sephadex LH-20 and high performance thin layer chromatography (HPTLC). The structures were identified by physico-chemical properties and spectral data. Result: Twenty-one compounds were isolated and purified as: N-trans-coumaroyltyramine(1)

N-trans-feruloyl-4'-O-methyldopamine(2)

p-hydroxybenzoic acid (3)

3

4-dimethoxy benzoic acid(4)

protocatechuate (5)

methyl 3

4-dihydroxybenzoate(6)

2-hydroxybenzoic acid(7)

ethyl 4-hydroxybenzoate(8)

ethyl 3

4-dihydroxybenzoate(9)

esculetin(10)

liquiritigenin(11)

hesperetin(12)

naringenin(13)

luteolin(14)

apigenin(15)

hrysoeriol(16)

diosmetin(17)

5

7-dihydroxy-3'

4'-dimethoxyflavone(18)

isoliavoues(19)

genistein(20)

and N-trans-feruloyltyramine(21). Conclusion: Compounds 1-20 were isolated from S. septemlobum and compounds 3-12 and 14-17 were obtained from Solanum for the first time. The literature review showed that amides and flavonoids had anti-inflammatory and antioxidant activities

providing a reference for further studies on pharmacodynamic material basis and the development and utilization of S. septemlobum from Xinjiang.