Objective: To study the clinical efficacy of Chaishao Chengqitang combined with low molecular heparin in treating hyperlipidemic pancreatitis (HLP) and the effect on inflammatory mediator

lipid and coagulation function. Method: Totally 167 cases of HLP patients treated in the Second Affiliated Hospital of Zhengzhou University from March 2014 to March 2016 were selected and divided into two groups according to the random number table

with 89 cases in clinical group and 88 in control group. Patients in both groups were treated with the routine therapy. In addition

the control group was also given low molecular heparin

while the clinical group was also given Chaishao Chengqitang. Then the treatment effect

clinical symptoms disappearance time

inflammatory mediator

lipid levels and coagulation function were compared. Result: Compared with 80.68% in the control group

the total effective rate of the clinical group was 93.25%. There was a significant difference (P<0.05). After treatment

the abdominal pain and distension disappearance time and gastrointestinal function

and blood urine amylase (AMY) recovery time were obviously shorter than those in control group. Compared with before treatment

interleukin-6(IL-6)

C-reaction protein (CRP)

tumor necrosis factor (TNF) -α of two groups after treatment decreased (P<0.05). Compared with control group

the values of TNF-α

IL-6

CRP and triglyceride (TG) in patients of clinical group were lower after treatment (P<0.05). After treatment

compared with before treatment

prothrombin time (PT) and activated partial thromboplastin time (APTT) of two groups were significantly increased. There were significant differences (P<0.05). Conclusion: Chaishao Chengqitang can significantly shorten the course of disease

reduce the expressions of serum inflammatory medium and blood lipid TG

and improve the patient's coagulative function. It has a better effect on HLP and is worth clinical application.