Objective: To explore the characteristics of traditional Chinese medicine(TCM) syndromes of the risk of the recurrent ischemic stroke. Method: The cases were selected from January 1st

2014 to December 31th

2015 in the chronic disease prevention and treatment information coordinate platform of the affiliated hospital to Changchun University of Chinese Medicine to start a cross-sectional study.Logistic multiple regression

generalized Boosted model and Wilcoxon rank sum test were used to discuss the influence of TCM syndromes and the syndrome factors on the recurrence of stroke. Result: In this study

3 322 cases were selected

including 1 542 cases of the new ischemic stroke and 1 780 cases of recurrent ischemic stroke.Characteristics of TCM syndromes manifested an important factor affecting the recurrence of ischemic stroke through generalized Boosted model.The result from Wilcoxon rank sum test showed that constituent rates of Qi deficiency and blood stasis syndrome

Yin deficiency and wind formation syndrome

upward disturbance of wind-fire syndrome and phlegm-heat and excessive Fu-viscera syndrome had statistical differences both in new and recurrence group(P<0.05

P<0.01);the constituent rates of phlegm

stasis and Qi deficiency in recurrence ischemic stroke were higher than the first ischemic stroke(P<0.01).Furthermore

Logistic multiple regression analysis was used to find that the performance of obstruction of collateral caused by windphlegm syndrome

Qi deficiency and blood stasis syndrome

phlegm-heat and excessive Fu-viscera syndrome

orifices confused by phlegm syndrome and phlegm-heat internal block syndrome may be the risk factor for the recurrence of ischemic stroke(P<0.05

P<0.01).All wind

fire

phlegm

stasis

Qi deficiency and Yin deficiency may also be a risk factor for the recurrence of ischemic stroke(P<0.05

P<0.01). Conclusion: Recurrence group of ischemic stroke manifests the characteristics of TCM syndromes.It indicates that the factors of the characteristics of TCM syndromes should be paid attention to in the stroke secondary prevention.It's necessary to be verified by means of evidence-based medicine and clinical practice.