Objective: In order to supply theoretical basis for clinical application of Tanreqing solution

in vitro deposition properties of 6 kinds of jet nebulizers were measured and compared. Method: The in vitro deposition properties of 6 kinds of jet nebulizers were determined by BRS2000 respiratory simulator and next generation impactor(NGI). Result: Delivery rates of Boy SX nebulizer with bule insert was 42.51 μg·min-1

it was the fastest among 6 kinds of jet nebulizers.The total delivery quantity of Boy SX nebulizer with red insert was 252.20 μg

it was the highest in 6 kinds of jet nebulizers.Different nebulizer had significant difference on total delivered dose(P<0.05).The amount of residue in inhalation solution cup of Boy SX nebulizer with red insert was the lowest (59.78 μg).The mass median aerodynamic diameter of aerosol measured with 6 kinds of nebulizers ranged from 3.57 μm to 4.98 μm.The mass median aerodynamic diameter and geometric standard deviation of Boy SX nebulizer with red insert were the lowest

but its effective deposition rate of fine particles was the highest. Conclusion: Particle size distribution of Boy SX nebulizer with red insert is the narrowest

and its fine particles have the most effective deposition rate;this nebulizer is most suitable for clinical use of Tanreqing inhalation solution.