Objective: To establish a GC-MS/MS method for detecting 179 pesticides in Citri Reticulatae Pericarpium

in order to find out the current situations of pesticide residues in Citri Reticulatae Pericarpium. Method: The samples were extracted with acetone for twice

cleaned up by solid-phase extraction (SPE)

concentrated

filtered

added with internal standard analysis protection agent

and then determined by GC-MS/MS. Result: The method of GC-MS/MS was established for determining 179 pesticides

including forbidden

limited

high-toxic and common pesticides. The recoveries of most pesticides ranged from 60% to 120%

with RSDs less than 15%. The limits of determination were below 0.01 mg·kg-1. Conclusion: This method is sensitive and accurate

and can be used for the determination of multi-residual pesticides in Citri Reticulatae Pericarpium. The findings show that many finds of pesticides were used in planting oranges

which causes serious pesticide residues pollution. Therefore

there is a risk of using Citri Reticulatae Pericarpium with excessive pesticide residues.