Bruguiera gymnorrhiza

a traditional Chinese medicinal mangrove plants

is mainly distributed in Guangdong

Guangxi

Fujian

Taiwan and its coastal islands

and grow in shallow sea salt beaches. According to the records of Chinese Ocean Materia Medica

its bark

used for sore throat

diarrhea

abdominal pain

bleeding caused by varied reasons

leaves for malaria

and fruits for proctoptosis due to long-term diarrhea

are of great value in pharmaceutical application. Profound researches on chemical composition and pharmacological actions has been increasingly implemented since the last century. The present studies have revealed that a variety of chemical compositions are found in extracted samples including flavonoids

sulfurations

terpenoids

aromatic compounds

cyanosides

amino acids

and 18 flavonoids

7 sulfurations

37 terpenoids

8 aromatic compounds

7 cyanosides

8 phenylpropanoids isolated from B. gymnorrhiza. Both in vivo and in vitro pharmacological studies have proved that these constituents have anti-inflammatory

anti-tumor

anti-oxidant

anti-fungal

anti-viral

anti-diabetic effects and are beneficial for cardiovascular diseases

but majority of the studies are focused on their antiviral and anti-tumor functions. Related literature in CNKI Database

Wanfang

Science Direct

PubMed and Web of science Database from 1972 to 2018 were research conditions of B. gymnorrhiza were summarized and explored the research progress on clinical medication

chemical composition

pharmacological activities by searching previous studies at home and abroad with respect to B. gymnorrhiza

hoping to provide the theoretical basis for its further studies and rational use in clinic.