YI Guo-hui, CHEN Jin-ping, WANG Li-li, et al. Analysis of Chemical Compositions and Antifungal Activity of Plant Essential Oils Against spp[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(22): 215-227.
YI Guo-hui, CHEN Jin-ping, WANG Li-li, et al. Analysis of Chemical Compositions and Antifungal Activity of Plant Essential Oils Against spp[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(22): 215-227. DOI: 10.13422/j.cnki.syfjx.20181714.
the incidence and mortality of clinical fungal infections have been increasing rapidly. Invasive fungal infections
especially candidiasis
have become the major cause. Currently
side effect have been found in many existing antifungal agents to different extents. In addition
with the extensive application of broad-spectrum antifungal agents in clinic
there has been a notable increase in drug resistance. Thus
it is very important to develop new and effective antifungal agents. Natural plant compositions
especially essential oils
have many beneficial biological activities
such as antibacterial
anti-inflammatory
antitumor and analgesic activities. They had already become a hotspot in the research and development of antifungal drugs
because of their advantages
such as wide sources
low toxicity
broad spectrum and diverse functions. The antifungal activity of essential oils is closely related to their components and contents. Therefore
in this paper
the progress of research on analysis of chemical compositions and antifungal activity of essential oils from different families of plants against Candida spp. was reviewed. Extraction and analysis of essential oils from Labiatae
Lauraceae
Myrtaceae and other plants were systematically summarized. Methods and mechanisms of action of anti-Candida activity were investigated. The direction of current studies was also discussed. All of these may provide a direction for the analysis and activity of essential oils in the future and lay the foundation for developing plant essential oils into new anti-Candida agents. It may also provide new solutions for clinical infections caused by drug resistance problems.