Objective:

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To explore drug utilizing regularity of traditional Chinese medicine(TCM) in treating and preventing asthenopia by analyzing the patent status of TCM in the field of asthenopia control for nearly 20 years.

Method:

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Global patents about TCM in treating and preventing asthenopia were systematic searched in IncoPat platform.The application trend

legal status and categories of patents were analyzed.Meanwhile

the oral prescriptions and external prescriptions were performed correlation index analysis by IBM SPSS Modeler 18.0

respectively; the difference of compatibility rules between them was compared.

Result:

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The number of global patents in treating and preventing asthenopia gradually increased

and the proportion of patents from China was more than 99%.The main patent applications were pharmaceutical composition

oral preparation

external eye patch and so on

but the ratio of licensed patents in total patents was low.In term of drug utilizing regularity

the oral prescriptions paid much attention to using TCM for nourishing the liver and kidney

while external prescriptions highlighted relieving sickness heat and detoxification.

Conclusion:

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Patents of TCM in treating and preventing asthenopia has been kept increasing in recent years

but the authorization rate is low.Formulation based on TCM theory can be statistically summarized

which can be helpful for the development of anti-asthenopia products.